Free radical reactions with simple biochemical systems
نویسندگان
چکیده
منابع مشابه
Physiological aspects of free-radical reactions.
Enzymes which catalyze the formation of free radicals in vitro will catalyze similar reactions in vivo. We believe that the formation of some kinds of free radicals has definite physiological meanings in metabolism. In this sense, the enzymes forming such free radicals are concluded to be in evolutionally advanced states. Elaborated structure and function of enzymes such as horseradish peroxida...
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Kinetic and mechanistic studies on some characteristic freeradica1 reactions are reviewed briefly. The unimolecular rearrangements: RCMe2CH ÷ Me2CCH2R, fall into two classes. Class 1: R = R'C(O)O for which the 1,2—migration occurs via a 5—eenter cyclic transition state with considerable charge separation, [R'C02 Me2CCH2]*. Class 2: R = H2C=CH, Me3CC=0, C6H5, Me3CCsC, and CsN, for which migratio...
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Oxidation of different types of 1,4-dihydropyridines with diphenylpicrylhydrazyl (DPP) and benzoyl peroxide (Bz2O2) as free radical oxidizing agents to pyridine derivatives is reported and a mechanism for this oxidation is also proposed.
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Titanium complexes have been widely used as catalysts for C‑C bond-forming processes via free-radical routes. Herein we provide an overview of some of the most significant contributions in the field, that covers the last decade, emphasizing the key role played by titanium salts in the promotion of selective reactions aimed at the synthesis of multifunctional organic compounds, including nucleop...
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Mechanisms of autoxidation of hemoglobin, and its reactions with H2O2, O2-, and oxidizing or reducing xenobiotics are discussed. Reactive intermediates of such reactions can include drug free radicals, H2O2, and O2-, as well as peroxidatively active ferrylhemoglobin and methemoglobin-H2O2. The contributions of these species to hemoglobin denaturation and drug-induced hemolysis, and the actions ...
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ژورنال
عنوان ژورنال: Journal of Chemical Education
سال: 1981
ISSN: 0021-9584,1938-1328
DOI: 10.1021/ed058p131